BAX anticorps (pThr167)

N° du produit ABIN1531490

L’anticorps Lapin Polyclonal anti-BAX a été validé pour ELISA et IF. Il convient pour détecter BAX dans des échantillons de Humain, Souris et Rat. Il y a 5+ publications disponibles.

Aperçu rapide pour BAX anticorps (pThr167) (ABIN1531490)

Antigène: BAX (BCL2-Associated X Protein (BAX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAX est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Détail du produit anti-BAX anticorps

Épitope: AA 133-182, pThr167

Specificité:

Bax (Phospho-Thr167) Antibody detects endogenous levels of Bax only when phosphorylated at Thr167.

PhosphorylationH:T167 M:T167 R:T167

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Thr167.

Isotype: IgG

Information d'application

Indications d'application: IF: 1:100~1:500 ELISA: 1:40000

Commentaires:

Unigene-Number: Hs.433670, Hs.631546 (NCBI Gene Symbol: BAX)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Références pour anticorps anti-BAX (ABIN1531490)

Grossini, Marotta, Farruggio, Sigaudo, Qoqaiche, Raina, de Giuli, Mary, Vacca, Pollastro: "Effects of Artemetin on Nitric Oxide Release and Protection against Peroxidative Injuries in Porcine Coronary Artery Endothelial Cells." dans: Phytotherapy research : PTR, (2015) (PubMed).

Grossini, Bellofatto, Farruggio, Sigaudo, Marotta, Raina, De Giuli, Mary, Pollesello, Minisini, Pirisi, Vacca: "Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0124742, (2015) (PubMed).

Grossini, Gramaglia, Farruggio, Bellofatto, Anchisi, Mary, Vacca, Zeppegno: "Asenapine increases nitric oxide release and protects porcine coronary artery endothelial cells against peroxidation." dans: Vascular pharmacology, Vol. 60, Issue 3, pp. 127-41, (2014) (PubMed).

Grossini, Pollesello, Bellofatto, Sigaudo, Farruggio, Origlia, Mombello, Mary, Valente, Vacca: "Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats." dans: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, Vol. 20, Issue 3, pp. 361-75, (2014) (PubMed).

Berger, Quast, Plötz, Kammermeier, Eberle: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." dans: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).

Détails sur BAX

Antigène: BAX (BCL2-Associated X Protein (BAX))

Autre désignation: Bax

Sujet:

Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4 , BAX , BCL2L4

NCBI Gene Symbol: BAX

Poids moléculaire: 21 kDa

ID gène: 581

OMIM: 600040

UniProt: Q07812

Pathways: Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response